SELECTED PUBLICATIONS

Excitatory microcircuits within superficial layers of the medial entorhinal cortex.
Winterer J, Maier N, Wozny C, Beed P, Breustedt J, Evangelista R, Peng Y, D'Albis T, Kempter R, Schmitz D.
Cell Reports. 2017 19:1110-1116.

Investigation of hippocampal synaptic transmission and plasticity in mice deficient in the actin-binding protein Drebrin.
Willmes CG, Mack TG, Ledderose J, Schmitz D, Wozny C, Eickholt BJ.
Sci Rep. 2017 Feb 15;7:42652.

Early Cortical Changes in Gamma Oscillations in Alzheimer's Disease.
Klein AS, Donoso JR, Kempter R, Schmitz D, Beed P.
Front Syst Neurosci. 2016 Oct 26;10:83.

RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.
Grauel MK, Maglione M, Reddy-Alla S, Willmes CG, Brockmann MM, Trimbuch T, Rosenmund T, Pangalos M, Vardar G, Stumpf A, Walter AM, Rost BR, Eickholt BJ, Haucke V, Schmitz D, Sigrist SJ, Rosenmund C.
Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11615-11620.

Human cerebrospinal fluid monoclonal N-methyl-D-aspartate receptor autoantibodies are sufficient for encephalitis pathogenesis.
Kreye J, Wenke NK, Chayka M, Leubner J, Murugan R, Maier N, Jurek B, Ly LT, Brandl D, Rost BR, Stumpf A, Schulz P, Radbruch H, Hauser AE, Pache F, Meisel A, Harms L, Paul F, Dirnagl U, Garner C, Schmitz D, Wardemann H, Prüss H.
Brain. 2016 Oct;139(Pt 10):2641-2652.

Cell-specific synaptic plasticity induced by network oscillations.
Zarnadze S, Bäuerle P, Santos-Torres J, Böhm C, Schmitz D, Geiger JR, Dugladze T, Gloveli T.
Elife. 2016 May 24;5.

Cannabinoid type 2 receptors mediate a cell type-specific plasticity in the hippocampus.
Stempel AV, Stumpf A, Zhang HY, Özdoğan T, Pannasch U, Theis AK, Otte DM, Wojtalla A, Rácz I, Ponomarenko A, Xi ZX, Zimmer A, Schmitz D.
Neuron. 2016 May 18;90(4):795-809.

Cellular and system biology of memory: timing, molecules, and beyond.
Schmitz D, Korte M.
Physiol Rev. 2016 Apr;96(2):647-93.

Functional architecture of the rat parasubiculum.
Tang Q*, Burgalossi A*, Ebbesen CL*, Sanguinetti-Scheck JI*, Schmidt H, Tukker JJ, Naumann R, Ray S, Preston-Ferrer P, Schmitz D, Brecht M.
J Neurosci. 2016 Feb 17;36(7):2289-301.

Optogenetic acidification of synaptic vesicles and lysosomes.
Rost BR, Schneider F, Grauel MK, Wozny C, G Bentz C, Blessing A, Rosenmund T, Jentsch TJ, Schmitz D, Hegemann P, Rosenmund C.
Nat Neurosci. 2015 Dec;18(12):1845-52.

Functional Diversity of Subicular Principal Cells during Hippocampal Ripples.
Böhm C, Peng Y, Maier N, Winterer J, Poulet JF, Geiger JR, Schmitz D.
J Neurosci. 2015 Oct 7;35(40):13608-18.

Anatomical organization and spatiotemporal firing patterns of layer 3 neurons in the rat medial entorhinal cortex.
Tang Q, Ebbesen CL, Sanguinetti-Scheck JI, Preston-Ferrer P, Gundlfinger A, Winterer J, Beed P, Ray S, Naumann R, Schmitz D, Brecht M, Burgalossi A.
J Neurosci. 2015 Sep 9;35(36):12346-54.

Ryanodine Receptor Activation Induces Long-Term Plasticity of Spine Calcium Dynamics.
Johenning FW, Theis AK, Pannasch U, Rückl M, Rüdiger S, Schmitz D.
PLoS Biol. 2015 Jun 22;13(6):e1002181.

Serotonin Attenuates Feedback Excitation onto O-LM Interneurons.
Böhm C, Pangalos M, Schmitz D*, Winterer J*.
Cereb Cortex. 2015 Nov;25(11):4572-83.

Retrograde signaling causes excitement.
Schmitz D, Breustedt J, Gundlfinger A.

Neuron. 2014 Feb 19;81(4):717-9.

Inhibitory gradient along the dorsoventral axis in the medial entorhinal cortex.
Beed P, Gundlfinger A, Schneiderbauer S, Song J, Böhm C, Burgalossi A, Brecht M, Vida I, Schmitz D.
Neuron. 2013 Sep 18;79(6):1197-207.

Role of RIM1α in short- and long-term synaptic plasticity at cerebellar parallel fibres.
Kintscher M, Wozny C, Johenning FW, Schmitz D, Breustedt J.
Nat Commun. 2013;4:2392.

Recruitment of oriens-lacunosum-moleculare interneurons during hippocampal ripples.
Pangalos M, Donoso JR, Winterer J, Zivkovic AR, Kempter R, Maier N*, Schmitz D*.
Proc Natl Acad Sci U S A. 2013 Mar 12;110(11):4398-403.

Segregation of axonal and somatic activity during fast network oscillations.
Dugladze T, Schmitz D, Whittington MA, Vida I, Gloveli T.
Science. 2012 Jun 15;336(6087):1458-61.

Coherent phasic excitation during hippocampal ripples.
Maier N*, Tejero-Cantero A*, Dorrn AL, Winterer J, Beed PS, Morris G, Kempter R, Poulet JF*, Leibold C*, Schmitz D*.
Neuron. 2011 Oct 6;72(1):137-52.

Complementary sensory and associative microcircuitry in primary olfactory cortex.
Wiegand HF, Beed P, Bendels MH, Leibold C, Schmitz D*, Johenning FW*.
J Neurosci. 2011 Aug 24;31(34):12149-58.

Cannabinoids disrupt hippocampal sharp wave-ripples via inhibition of glutamate release.
Maier N, Morris G, Schuchmann S, Korotkova T, Ponomarenko A, Böhm C, Wozny C, Schmitz D.
Hippocampus. 2012 Jun;22(6):1350-62.

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2.
Schmeisser MJ, Ey E, Wegener S, Bockmann J, Stempel AV, Kuebler A, Janssen AL, Udvardi PT, Shiban E, Spilker C, Balschun D, Skryabin BV, Dieck St, Smalla KH, Montag D, Leblond CS, Faure P, Torquet N, Le Sourd AM, Toro R, Grabrucker AM, Shoichet SA, Schmitz D, Kreutz MR, Bourgeron T, Gundelfinger ED, Boeckers TM.
Nature. 2012 Apr 29;486(7402):256-60.

Activation of metabotropic GABA receptors increases the energy barrier for vesicle fusion.
Rost BR, Nicholson P, Ahnert-Hilger G, Rummel A, Rosenmund C, Breustedt J*, Schmitz D*.
J Cell Sci. 2011 Sep 15;124(Pt 18):3066-73.

Cell-type-specific modulation of feedback inhibition by serotonin in the hippocampus.
Winterer J, Stempel AV, Dugladze T, Földy C, Maziashvili N, Zivkovic AR, Priller J, Soltesz I, Gloveli T, Schmitz D.
J Neurosci. 2011 Jun 8;31(23):8464-75.

Muskelin regulates actin filament- and microtubule-based GABA(A) receptor transport in neurons.
Heisler FF, Loebrich S, Pechmann Y, Maier N, Zivkovic AR, Tokito M, Hausrat TJ, Schweizer M, Bähring R, Holzbaur EL, Schmitz D, Kneussel M.
Neuron. 2011 Apr 14;70(1):66-81.

Analysis of excitatory microcircuitry in the medial entorhinal cortex reveals cell-type-specific differences.
Beed P*, Bendels MH*, Wiegand HF, Leibold C, Johenning FW*, Schmitz D*.
Neuron. 2010 Dec 22;68(6):1059-66.

GluK1 inhibits calcium dependent and independent transmitter release at associational/commissural synapses in area CA3 of the hippocampus.
Salmen B, Beed PS, Ozdogan T, Maier N, Johenning FW, Winterer J, Breustedt J, Schmitz D.
Hippocampus. 2012 Jan;22(1):57-68.

Autaptic cultures of single hippocampal granule cells of mice and rats.
Rost BR, Breustedt J, Schoenherr A, Grosse G, Ahnert-Hilger G, Schmitz D.
Eur J Neurosci. 2010 Sep;32(6):939-47.

Detection of input sites in scanning photostimulation data based on spatial correlations.
Bendels MH, Beed P, Schmitz D, Johenning FW, Leibold C.
J Neurosci Methods. 2010 Oct 15;192(2):286-95.

Munc13-2 differentially affects hippocampal synaptic transmission and plasticity.
Breustedt J, Gundlfinger A, Varoqueaux F, Reim K, Brose N, Schmitz D.
Cereb Cortex. 2010 May;20(5):1109-20.

Natural spike trains trigger short- and long-lasting dynamics at hippocampal mossy fiber synapses in rodents.
Gundlfinger A*, Breustedt J*, Sullivan D, Schmitz D.
PLoS One. 2010 Apr 1;5(4):e9961.

Dendritic compartment and neuronal output mode determine pathway-specific long-term potentiation in the piriform cortex.
Johenning FW, Beed PS, Trimbuch T, Bendels MH, Winterer J, Schmitz D.
J Neurosci. 2009 Oct 28;29(43):13649-61.

An approach for reliably investigating hippocampal sharp wave-ripples in vitro.
Maier N, Morris G, Johenning FW, Schmitz D.
PLoS One. 2009 Sep 7;4(9):e6925.

The function of glutamatergic synapses is not perturbed by severe knockdown of 4.1N and 4.1G expression.
Wozny C*, Breustedt J*, Wolk F*, Varoqueaux F, Boretius S, Zivkovic AR, Neeb A, Frahm J, Schmitz D, Brose N, Ivanovic A.
J Cell Sci. 2009 Mar 1;122(Pt 5):735-44.

Differential cAMP signaling at hippocampal output synapses.
Wozny C*, Maier N*, Fidzinski P, Breustedt J, Behr J*, Schmitz D*.
J Neurosci. 2008 Dec 31;28(53):14358-62.

A novel control software that improves the experimental workflow of scanning photostimulation experiments.
Bendels MH*, Beed P*, Leibold C, Schmitz D*, Johenning FW*.
J Neurosci Methods. 2008 Oct 30;175(1):44-57.

Two different forms of long-term potentiation at CA1-subiculum synapses.
Wozny C, Maier N, Schmitz D, Behr J.
J Physiol. 2008 Jun 1;586(Pt 11):2725-34

Differential modulation of short-term synaptic dynamics by long-term potentiation at mouse hippocampal mossy fibre synapses.
Gundlfinger A*, Leibold C*, Gebert K, Moisel M, Schmitz D*, Kempter R*.
J Physiol. 2007 Dec 15;585(Pt 3):853-65.

Adenosine modulates transmission at the hippocampal mossy fibre synapse via direct inhibition of presynaptic calcium channels.
Gundlfinger A, Bischofberger J, Johenning FW, Torvinen M, Schmitz D*, Breustedt J*.
J Physiol. 2007 Jul 1;582(Pt 1):263-77.

Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories.
Plath N*, Ohana O*, Dammermann B, Errington ML, Schmitz D, Gross C, Mao X, Engelsberg A, Mahlke C, Welzl H, Kobalz U, Stawrakakis A, Fernandez E, Waltereit R, Bick-Sander A, Therstappen E, Cooke SF, Blanquet V, Wurst W, Salmen B, Bösl MR, Lipp HP, Grant SG, Bliss TV, Wolfer DP, Kuhl D.
Neuron. 2006 Nov 9;52(3):437-44.

Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis.
Schuchmann S*, Schmitz D*, Rivera C, Vanhatalo S, Salmen B, Mackie K, Sipilä ST, Voipio J, Kaila K.
Nat Med. 2006 Jul;12(7):817-23.

Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.
Breustedt J, Schmitz D.
J Neurosci. 2004 Nov 10;24(45):10093-8.

Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses.
Moore KA, Nicoll RA, Schmitz D.
Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14397-402.

Alpha1E-containing Ca2+ channels are involved in synaptic plasticity.
Breustedt J, Vogt KE, Miller RJ, Nicoll RA, Schmitz D.
Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12450-5.

Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation.
Schmitz D*, Mellor J*, Breustedt J, Nicoll RA.
Nat Neurosci. 2003 Oct;6(10):1058-63.

Mediation of hippocampal mossy fiber long-term potentiation by presynaptic Ih channels.
Mellor J, Nicoll RA, Schmitz D.
Science. 2002 Jan 4;295(5552):143-7.

Axo-axonal coupling. a novel mechanism for ultrafast neuronal communication.
Schmitz D, Schuchmann S, Fisahn A, Draguhn A, Buhl EH, Petrasch-Parwez E, Dermietzel R, Heinemann U, Traub RD.
Neuron. 2001 Sep 13;31(5):831-40.

Synaptic and nonsynaptic contributions to giant ipsps and ectopic spikes induced by 4-aminopyridine in the hippocampus in vitro.
Traub RD, Bibbig R, Piechotta A, Draguhn R, Schmitz D.
J Neurophysiol. 2001 Mar;85(3):1246-56.

Presynaptic kainate receptor mediation of frequency facilitation at hippocampal mossy fiber synapses.
Schmitz D, Mellor J, Nicoll RA.
Science. 2001 Mar 9;291(5510):1972-6.

Synaptic activation of presynaptic kainate receptors on hippocampal mossy fiber synapses.
Schmitz D, Frerking M, Nicoll RA.
Neuron. 2000 Aug;27(2):327-38.

Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro.
Draguhn A, Traub RD, Schmitz D, Jefferys JG.
Nature. 1998 Jul 9;394(6689):189-92.

 

* equal contribution authorship